Cargando…

Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF

Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological activities. It was first identified as a neurotrophic factor and later as the most potent natural antiangiogenic factor, a stem cell niche factor, and an inhibitor of cancer cell growth. Numerous animal models de...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Guo, Zhong, Ming, Kawaguchi, Riki, Kassai, Miki, Al-Ubaidi, Muayyad, Deng, Jun, Ter-Stepanian, Mariam, Sun, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303762/
https://www.ncbi.nlm.nih.gov/pubmed/25535841
http://dx.doi.org/10.7554/eLife.05401