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Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF
Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological activities. It was first identified as a neurotrophic factor and later as the most potent natural antiangiogenic factor, a stem cell niche factor, and an inhibitor of cancer cell growth. Numerous animal models de...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303762/ https://www.ncbi.nlm.nih.gov/pubmed/25535841 http://dx.doi.org/10.7554/eLife.05401 |