Cargando…

Discovery of Highly Potent Tyrosinase Inhibitor, T1, with Significant Anti-Melanogenesis Ability by zebrafish in vivo Assay and Computational Molecular Modeling

Tyrosinase is involved in melanin biosynthesis and the abnormal accumulation of melanin pigments leading to hyperpigmentation disorders that can be treated with depigmenting agents. A natural product T1, bis(4-hydroxybenzyl)sulfide, isolated from the Chinese herbal plant, Gastrodia elata, is a stron...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Wang-Chuan, Tseng, Tien-Sheng, Hsiao, Nai-Wan, Lin, Yun-Lian, Wen, Zhi-Hong, Tsai, Chin-Chuan, Lee, Yu-Ching, Lin, Hui-Hsiung, Tsai, Keng-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303873/ https://www.ncbi.nlm.nih.gov/pubmed/25613357 http://dx.doi.org/10.1038/srep07995

Ejemplares similares

Fermented Broth in Tyrosinase- and Melanogenesis Inhibition
por: Chan, Chin-Feng, et al.
Publicado: (2014)

Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties
por: Noori, Milad, et al.
Publicado: (2023)

Kinetics of Mushroom Tyrosinase and Melanogenesis Inhibition by N-Acetyl-pentapeptides
por: Lien, Ching-Yi, et al.
Publicado: (2014)

Tyrosinase Nanoparticles: Understanding the Melanogenesis Pathway by Isolating the Products of Tyrosinase Enzymatic Reaction
por: Varghese, Paul K., et al.
Publicado: (2021)

Urolithin and Reduced Urolithin Derivatives as Potent Inhibitors of Tyrosinase and Melanogenesis: Importance of the 4-Substituted Resorcinol Moiety
por: Lee, Sanggwon, et al.
Publicado: (2021)

Influence of plasma-activated compounds on melanogenesis and tyrosinase activity
por: Ali, Anser, et al.
Publicado: (2016)

Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo
por: Niu, Chao, et al.
Publicado: (2017)

Maclurin Exhibits Antioxidant and Anti-Tyrosinase Activities, Suppressing Melanogenesis
por: Moon, Kyoung Mi, et al.
Publicado: (2022)

Inhibitory Effect of Curcumin-Inspired Derivatives on Tyrosinase Activity and Melanogenesis
por: Rocchitta, Gaia, et al.
Publicado: (2022)

Effect of Vetiveria zizanioides Essential Oil on Melanogenesis in Melanoma Cells: Downregulation of Tyrosinase Expression and Suppression of Oxidative Stress
por: Peng, Hsin-Yi, et al.
Publicado: (2014)

Natural Melanogenesis Inhibitors Acting Through the Down-Regulation of Tyrosinase Activity
por: Chang, Te-Sheng
Publicado: (2012)

Tyrosinase-Targeting Gallacetophenone Inhibits Melanogenesis in Melanocytes and Human Skin- Equivalents
por: Lee, Ji Young, et al.
Publicado: (2020)

Biochemistry of melanin synthesis: in vivo effects of MSH on tyrosinase and melanogenesis of pigmentary system.
por: Lee, T. H., et al.
Publicado: (1973)

Brassinin Abundant in Brassicaceae Suppresses Melanogenesis through Dual Mechanisms of Tyrosinase Inhibition
por: Lee, Min-Kyeong, et al.
Publicado: (2022)

The effect of Aspalathus linearis (Burm.f.) R.Dahlgren and its compounds on tyrosinase and melanogenesis
por: Blom van Staden, Analike, et al.
Publicado: (2021)

Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis
por: Nazir, Yasir, et al.
Publicado: (2022)

Extract of Ganoderma formosanum Mycelium as a Highly Potent Tyrosinase Inhibitor
por: Hsu, Kai-Di, et al.
Publicado: (2016)

Melanogenesis-Inducing Effect of Cirsimaritin through Increases in Microphthalmia-Associated Transcription Factor and Tyrosinase Expression
por: Kim, Hyo Jung, et al.
Publicado: (2015)

Modified Riceberry rice extract suppresses melanogenesis-associated cell differentiation through tyrosinase-mediated MITF downregulation on B16 cells and in vivo zebrafish embryos
por: Rodboon, Teerapat, et al.
Publicado: (2020)

New Benzimidazothiazolone Derivatives as Tyrosinase Inhibitors with Potential Anti-Melanogenesis and Reactive Oxygen Species Scavenging Activities
por: Jung, Hee Jin, et al.
Publicado: (2021)

Evaluation of the Antioxidant and Melanogenesis Inhibitory Properties of Pracparatum Mungo (Lu-Do Huang)
por: Kao, Yu-Yu, et al.
Publicado: (2013)

Effect of Adenosine on Melanogenesis in B16 Cells and Zebrafish
por: Kim, Mi Yoon, et al.
Publicado: (2014)

Oenothera laciniata Hill Extracts Exhibits Antioxidant Effects and Attenuates Melanogenesis in B16-F10 Cells via Downregulating CREB/MITF/Tyrosinase and Upregulating p-ERK and p-JNK
por: Ko, Horng-Huey, et al.
Publicado: (2021)

The lactoferricin B-derived peptide, LfB17-34, induces melanogenesis in B16F10 cells
por: Huang, Hsiu-Chin, et al.
Publicado: (2017)

Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis
por: Lai, Xuelei, et al.
Publicado: (2017)

Synergistic effects of novel herbal decoctions from Panax ginseng and Morus alba on tyrosinase activity and melanogenesis in vitro
por: Kim, Ji Hye, et al.
Publicado: (2022)

Discovery Sulfoglycomics and Identification of the Characteristic Fragment Ions for High-Sensitivity Precise Mapping of Adult Zebrafish Brain–Specific Glycotopes
por: Tseng, Huan-Chuan, et al.
Publicado: (2021)

Synthesis of Novel Compounds as New Potent Tyrosinase Inhibitors
por: Hamidian, Hooshang
Publicado: (2013)

Extracts from European Propolises as Potent Tyrosinase Inhibitors
por: Widelski, Jarosław, et al.
Publicado: (2022)

N-(4-methoxyphenyl) caffeamide-induced melanogenesis inhibition mechanisms
por: Kuo, Yueh-Hsiung, et al.
Publicado: (2017)

Preventive Effect of M. cochinchinensis on Melanogenesis via Tyrosinase Activity Inhibition and p-PKC Signaling in Melan-A Cell
por: Kim, Juyong, et al.
Publicado: (2021)

Chemical Constituents, Antioxidant, Anti-Tyrosinase, Cytotoxicity, and Anti-Melanogenesis Activities of Etlingera elatior (Jack) Leaf Essential Oils
por: Sangthong, Sarita, et al.
Publicado: (2022)

Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies
por: Abbas, Qamar, et al.
Publicado: (2017)

Thyroid Hormones Regulate Zebrafish Melanogenesis in a Gender-Specific Manner
por: Guillot, Raúl, et al.
Publicado: (2016)

Plants from Brazilian Cerrado with Potent Tyrosinase Inhibitory Activity
por: Souza, Paula Monteiro, et al.
Publicado: (2012)

Diarylalkanoids as Potent Tyrosinase Inhibitors from the Stems of Semecarpus caudata
por: Dang, Phu H., et al.
Publicado: (2021)

Plumbagin Suppresses α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells by Inhibiting Tyrosinase Activity
por: Oh, Taek-In, et al.
Publicado: (2017)

Inhibition of melanogenesis by jineol from Scolopendra subspinipes mutilans via MAP-Kinase mediated MITF downregulation and the proteasomal degradation of tyrosinase
por: Alam, Md Badrul, et al.
Publicado: (2017)

Evaluation of TILI-2 as an Anti-Tyrosinase, Anti-Oxidative Agent and Its Role in Preventing Melanogenesis Using a Proteomics Approach
por: Joompang, Anupong, et al.
Publicado: (2022)

Hirsutanone Isolated from the Bark of Alnus japonica Attenuates Melanogenesis via Dual Inhibition of Tyrosinase Activity and Expression of Melanogenic Proteins
por: Uto, Takuhiro, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2ld5une22c2m9r8m6n580q0dab