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Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia
Selective elimination of synaptic connections is a common phenomenon which occurs during both developmental and pathological conditions. Glial cells have a central role in the pruning of synapses by specifically engulfing the degenerating neurites of inappropriate connections, but its regulatory mec...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303875/ https://www.ncbi.nlm.nih.gov/pubmed/25612542 http://dx.doi.org/10.1038/srep07989 |