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Optimal microdomain crosstalk between endoplasmic reticulum and mitochondria for Ca(2+) oscillations
A Ca(2+) signaling model is proposed to consider the crosstalk of Ca(2+) ions between endoplasmic reticulum (ER) and mitochondria within microdomains around inositol 1, 4, 5-trisphosphate receptors (IP(3)R) and the mitochondrial Ca(2+) uniporter (MCU). Our model predicts that there is a critical IP(...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303883/ https://www.ncbi.nlm.nih.gov/pubmed/25614067 http://dx.doi.org/10.1038/srep07984 |