Optimal microdomain crosstalk between endoplasmic reticulum and mitochondria for Ca(2+) oscillations

A Ca(2+) signaling model is proposed to consider the crosstalk of Ca(2+) ions between endoplasmic reticulum (ER) and mitochondria within microdomains around inositol 1, 4, 5-trisphosphate receptors (IP(3)R) and the mitochondrial Ca(2+) uniporter (MCU). Our model predicts that there is a critical IP(...

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Detalles Bibliográficos
Autores principales: Qi, Hong, Li, Linxi, Shuai, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303883/
https://www.ncbi.nlm.nih.gov/pubmed/25614067
http://dx.doi.org/10.1038/srep07984

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