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Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation

Precise regulation of mtDNA transcription and oxidative phosphorylation (OXPHOS) is crucial for human health. As a component of mitochondrial contact site and cristae organizing system (MICOS), Mic60 plays a central role in mitochondrial morphology. However, it remains unclear whether Mic60 affects...

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Detalles Bibliográficos
Autores principales: Yang, Rui-Feng, Sun, Li-Hong, Zhang, Ran, Zhang, Yuan, Luo, Yu-Xuan, Zheng, Wei, Zhang, Zhu-Qin, Chen, Hou-Zao, Liu, De-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303897/
https://www.ncbi.nlm.nih.gov/pubmed/25612828
http://dx.doi.org/10.1038/srep07990