Cargando…
Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation
Precise regulation of mtDNA transcription and oxidative phosphorylation (OXPHOS) is crucial for human health. As a component of mitochondrial contact site and cristae organizing system (MICOS), Mic60 plays a central role in mitochondrial morphology. However, it remains unclear whether Mic60 affects...
Autores principales: | Yang, Rui-Feng, Sun, Li-Hong, Zhang, Ran, Zhang, Yuan, Luo, Yu-Xuan, Zheng, Wei, Zhang, Zhu-Qin, Chen, Hou-Zao, Liu, De-Pei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303897/ https://www.ncbi.nlm.nih.gov/pubmed/25612828 http://dx.doi.org/10.1038/srep07990 |
Ejemplares similares
-
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy
por: Dong, Tingting, et al.
Publicado: (2023) -
Drosophila MIC60/mitofilin conducts dual roles in mitochondrial motility and crista structure
por: Tsai, Pei-I, et al.
Publicado: (2017) -
Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
por: Hessenberger, Manuel, et al.
Publicado: (2017) -
Structural insights into crista junction formation by the Mic60-Mic19 complex
por: Bock-Bierbaum, Tobias, et al.
Publicado: (2022) -
Effects of Aging on Expression of Mic60 and OPA1 and Mitochondrial Morphology in Myocardium of Tibetan Sheep
por: Wang, Guan, et al.
Publicado: (2020)