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A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: Evidence for passive and facilitated transport
The gill is the principle site of xenobiotic transfer to and from the aqueous environment. To replace, refine or reduce (3Rs) the large numbers of fish used in in vivo uptake studies an effective in vitro screen is required that mimics the function of the teleost gill. This study uses a rainbow trou...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier/North Holland Biomedical Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303912/ https://www.ncbi.nlm.nih.gov/pubmed/25544062 http://dx.doi.org/10.1016/j.aquatox.2014.12.007 |