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Distance-based classifiers as potential diagnostic and prediction tools for human diseases

Typically, gene expression biomarkers are being discovered in course of high-throughput experiments, for example, RNAseq or microarray profiling. Analytic pipelines that extract so-called signatures suffer from the "Dimensionality curse": the number of genes expressed exceeds the number of...

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Detalles Bibliográficos
Autores principales: Veytsman, Boris, Wang, Lei, Cui, Tiange, Bruskin, Sergey, Baranova, Ancha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303935/
https://www.ncbi.nlm.nih.gov/pubmed/25563076
http://dx.doi.org/10.1186/1471-2164-15-S12-S10