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Application of quantitative trait locus mapping and transcriptomics to studies of the senescence-accelerated phenotype in rats

BACKGROUND: Etiology of complex disorders, such as cataract and neurodegenerative diseases including age-related macular degeneration (AMD), remains poorly understood due to the paucity of animal models, fully replicating the human disease. Previously, two quantitative trait loci (QTLs) associated w...

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Detalles Bibliográficos
Autores principales: Korbolina, Elena E, Ershov, Nikita I, Bryzgalov, Leonid O, Kolosova, Natalia G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303943/
https://www.ncbi.nlm.nih.gov/pubmed/25563673
http://dx.doi.org/10.1186/1471-2164-15-S12-S3