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Application of quantitative trait locus mapping and transcriptomics to studies of the senescence-accelerated phenotype in rats
BACKGROUND: Etiology of complex disorders, such as cataract and neurodegenerative diseases including age-related macular degeneration (AMD), remains poorly understood due to the paucity of animal models, fully replicating the human disease. Previously, two quantitative trait loci (QTLs) associated w...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303943/ https://www.ncbi.nlm.nih.gov/pubmed/25563673 http://dx.doi.org/10.1186/1471-2164-15-S12-S3 |