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Analysis of discordant Affymetrix probesets casts serious doubt on idea of microarray data reutilization

BACKGROUND: Affymetrix microarray technology allows one to investigate expression of thousands of genes simultaneously upon a variety of conditions. In a popular U133A microarray platform, the expression of 37% of genes is measured by more than one probeset. The discordant expression observed for tw...

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Detalles Bibliográficos
Autores principales: Marakhonov, Andrey, Sadovskaya, Nataliya, Antonov, Ivan, Baranova, Ancha, Skoblov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303952/
https://www.ncbi.nlm.nih.gov/pubmed/25563078
http://dx.doi.org/10.1186/1471-2164-15-S12-S8