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Dynamics of miRNA driven feed-forward loop depends upon miRNA action mechanisms

BACKGROUND: We perform the theoretical analysis of a gene network sub-system, composed of a feed-forward loop, in which the upstream transcription factor regulates the target gene via two parallel pathways: directly, and via interaction with miRNA. RESULTS: As the molecular mechanisms of miRNA actio...

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Detalles Bibliográficos
Autores principales: Duk, Maria A, Samsonova, Maria G, Samsonov, Alexander M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303955/
https://www.ncbi.nlm.nih.gov/pubmed/25563303
http://dx.doi.org/10.1186/1471-2164-15-S12-S9