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Population Pharmacokinetics of Ceftolozane/Tazobactam in Healthy Volunteers, Subjects With Varying Degrees of Renal Function and Patients With Bacterial Infections

Ceftolozane/tazobactam is a novel antipseudomonal cephalosporin and β-lactamase inhibitor in clinical development for treatment of complicated urinary tract (cUTI) and intra-abdominal (cIAI) infections and nosocomial pneumonia. The population pharmacokinetics of ceftolozane/tazobactam were character...

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Detalles Bibliográficos
Autores principales: Chandorkar, Gurudatt, Xiao, Alan, Mouksassi, Mohamad-Samer, Hershberger, Ellie, Krishna, Gopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303958/
https://www.ncbi.nlm.nih.gov/pubmed/25196976
http://dx.doi.org/10.1002/jcph.395