ATGL-Catalyzed Lipolysis Regulates SIRT1 to Control PGC-1α/PPAR-α Signaling

Sirtuin 1 (SIRT1), an NAD(+)-dependent protein deacetylase, regulates a host of target proteins, including peroxisome proliferator–activated receptor (PPAR)-γ coactivator-1α (PGC-1α), a transcriptional coregulator that binds to numerous transcription factors in response to deacetylation to promote m...

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Detalles Bibliográficos
Autores principales: Khan, Salmaan Ahmed, Sathyanarayan, Aishwarya, Mashek, Mara T., Ong, Kuok Teong, Wollaston-Hayden, Edith E., Mashek, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303962/
https://www.ncbi.nlm.nih.gov/pubmed/25614670
http://dx.doi.org/10.2337/db14-0325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303962/
https://www.ncbi.nlm.nih.gov/pubmed/25614670
http://dx.doi.org/10.2337/db14-0325

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