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Detection of ALK protein expression in lung squamous cell carcinomas by immunohistochemistry
BACKGROUND: The echinoderm microtubule-associated protein-like 4 (EML4) gene and the anaplastic lymphoma kinase (ALK) gene rearrangements occur in approximately 5% of lung adenocarcimomas (ACA), leading to ALK overexpression and predicting response to targeted therapy. To the present, few studies ha...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304180/ https://www.ncbi.nlm.nih.gov/pubmed/25527865 http://dx.doi.org/10.1186/s13046-014-0109-2 |