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Detection of ALK protein expression in lung squamous cell carcinomas by immunohistochemistry

BACKGROUND: The echinoderm microtubule-associated protein-like 4 (EML4) gene and the anaplastic lymphoma kinase (ALK) gene rearrangements occur in approximately 5% of lung adenocarcimomas (ACA), leading to ALK overexpression and predicting response to targeted therapy. To the present, few studies ha...

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Detalles Bibliográficos
Autores principales: Wang, Jiandong, Shen, Qin, Shi, Qunli, Yu, Bo, Wang, Xuan, Cheng, Kai, Lu, Guangming, Zhou, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304180/
https://www.ncbi.nlm.nih.gov/pubmed/25527865
http://dx.doi.org/10.1186/s13046-014-0109-2