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Protein sector analysis for the clustering of disease-associated mutations
BACKGROUND: The importance of mutations in disease phenotype has been studied, with information available in databases such as OMIM. However, it remains a research challenge for the possibility of clustering amino acid residues based on an underlying interaction, such as co-evolution, to understand...
Autores principales: | Guevara-Coto, Jose, Schwartz, Charles E, Wang, Liangjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304181/ https://www.ncbi.nlm.nih.gov/pubmed/25559331 http://dx.doi.org/10.1186/1471-2164-15-S11-S4 |
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