Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

BACKGROUND: DNA methylomes are extensively reprogrammed during mouse pre-implantation and early germ cell development. The main feature of this reprogramming is a genome-wide decrease in 5-methylcytosine (5mC). Standard high-resolution single-stranded bisulfite sequencing techniques do not allow dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Arand, Julia, Wossidlo, Mark, Lepikhov, Konstantin, Peat, Julian R, Reik, Wolf, Walter, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304184/
https://www.ncbi.nlm.nih.gov/pubmed/25621012
http://dx.doi.org/10.1186/1756-8935-8-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304184/
https://www.ncbi.nlm.nih.gov/pubmed/25621012
http://dx.doi.org/10.1186/1756-8935-8-1

Ejemplares similares