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Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma

BACKGROUND: Pim-1 (Provirus integration site for Moloney murine leukemia virus 1) belongs to the Ser/Thr kinase family and plays a pivotal role in occurrence and development of oncogenesis. Recent studies have demonstrated that Pim-1 phosphorylates RUNX3 and alters its subcellular localization. Howe...

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Detalles Bibliográficos
Autores principales: Zhu, Xin, Xu, Jia-jie, Hu, Si-si, Feng, Jian-guo, Jiang, Lie-hao, Hou, Xiu-xiu, Cao, Jun, Han, Jing, Ling, Zhi-qiang, Ge, Ming-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304190/
https://www.ncbi.nlm.nih.gov/pubmed/25551195
http://dx.doi.org/10.1186/s13046-014-0114-5