KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity

BACKGROUND: Hormone-refractory prostate cancer (HRPC), which is resistant to hormone therapy, is a major obstacle in clinical treatment. An approach to inhibit HRPC growth and ultimately to kill cancers is highly demanded. RESULTS: KUD773 induced the anti-proliferative effect and subsequent apoptosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Chia-Chun, Liu, Shih-Ping, Hsu, Jui-Ling, Hsu, John TA, Kudryavtsev, Konstantin V, Guh, Jih-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304192/
https://www.ncbi.nlm.nih.gov/pubmed/25563361
http://dx.doi.org/10.1186/s12929-014-0107-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304192/
https://www.ncbi.nlm.nih.gov/pubmed/25563361
http://dx.doi.org/10.1186/s12929-014-0107-x

Ejemplares similares