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A common feature pharmacophore for FDA-approved drugs inhibiting the Ebola virus

We are currently faced with a global infectious disease crisis which has been anticipated for decades. While many promising biotherapeutics are being tested, the search for a small molecule has yet to deliver an approved drug or therapeutic for the Ebola or similar filoviruses that cause haemorrhagi...

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Detalles Bibliográficos
Autores principales: Ekins, Sean, Freundlich, Joel S., Coffee, Megan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304229/
https://www.ncbi.nlm.nih.gov/pubmed/25653841
http://dx.doi.org/10.12688/f1000research.5741.2