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Metal-catalyzed uncaging of DNA-binding agents in living cells

Attachment of alloc protecting groups to the amidine units of fluorogenic DNA-binding bisbenzamidines or to the amino groups of ethidium bromide leads to a significant reduction of their DNA affinity. More importantly, the active DNA-binding species can be readily regenerated by treatment with ruthe...

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Detalles Bibliográficos
Autores principales: Sánchez, Mateo I., Penas, Cristina, Vázquez, M. Eugenio, Mascareñas, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304260/
https://www.ncbi.nlm.nih.gov/pubmed/25632343
http://dx.doi.org/10.1039/c3sc53317d