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Disparate roles of zinc in chemical hypoxia-induced neuronal death
Accumulating evidence has provided a causative role of zinc (Zn(2+)) in neuronal death following ischemic brain injury. Using a hypoxia model of primary cultured cortical neurons with hypoxia-inducing chemicals, cobalt chloride (1 mM CoCl(2)), deferoxamine (3 mM DFX), and sodium azide (2 mM NaN(3)),...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304355/ https://www.ncbi.nlm.nih.gov/pubmed/25667569 http://dx.doi.org/10.3389/fncel.2015.00001 |