Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity

Immune responses must be well restrained in a steady state to avoid excessive inflammation. However, such restraints are quickly removed to exert anti-microbial responses. Here, we report a role of autophagy in an early host anti-fungal response by enhancing NFκB activity through A20 sequestration....

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Detalles Bibliográficos
Autores principales: Kanayama, Masashi, Inoue, Makoto, Danzaki, Keiko, Hammer, Gianna, He, You-Wen, Shinohara, Mari L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304414/
https://www.ncbi.nlm.nih.gov/pubmed/25609235
http://dx.doi.org/10.1038/ncomms6779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304414/
https://www.ncbi.nlm.nih.gov/pubmed/25609235
http://dx.doi.org/10.1038/ncomms6779

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