Substoichiometric Hydroxynonenylation of a Single Protein Recapitulates Whole-Cell-Stimulated Antioxidant Response

[Image: see text] Lipid-derived electrophiles (LDEs) that can directly modify proteins have emerged as important small-molecule cues in cellular decision-making. However, because these diffusible LDEs can modify many targets [e.g., >700 cysteines are modified by the well-known LDE 4-hydroxynonena...

Descripción completa

Detalles Bibliográficos
Autores principales: Parvez, Saba, Fu, Yuan, Li, Jiayang, Long, Marcus J. C., Lin, Hong-Yu, Lee, Dustin K., Hu, Gene S., Aye, Yimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304447/
https://www.ncbi.nlm.nih.gov/pubmed/25544059
http://dx.doi.org/10.1021/ja5084249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304447/
https://www.ncbi.nlm.nih.gov/pubmed/25544059
http://dx.doi.org/10.1021/ja5084249

Ejemplares similares