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Inhibition of MiR-199a-5p Reduced Cell Proliferation in Autosomal Dominant Polycystic Kidney Disease through Targeting CDKN1C

BACKGROUND: With a prevalence of about 1:500 to 1:1,000, autosomal dominant polycystic kidney disease (ADPKD) often causes renal failure, with many serious complications. However, there is no Food and Drug Administration (FDA) approved therapy available. MATERIAL/METHODS: MiR-199a-5p level in ADPKD...

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Detalles Bibliográficos
Autores principales: Sun, Lijun, Zhu, Jiaqi, Wu, Ming, Sun, Haipeng, Zhou, Chenchen, Fu, Lili, Xu, Chenggang, Mei, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304454/
https://www.ncbi.nlm.nih.gov/pubmed/25588980
http://dx.doi.org/10.12659/MSM.892141