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Catalytic Spectrum of the Penicillin-Binding Protein 4 of Pseudomonas aeruginosa, a Nexus for the Induction of β-Lactam Antibiotic Resistance

[Image: see text] Pseudomonas aeruginosa is an opportunistic Gram-negative bacterial pathogen. A primary contributor to its ability to resist β-lactam antibiotics is the expression, following detection of the β-lactam, of the AmpC β-lactamase. As AmpC expression is directly linked to the recycling o...

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Detalles Bibliográficos
Autores principales: Lee, Mijoon, Hesek, Dusan, Blázquez, Blas, Lastochkin, Elena, Boggess, Bill, Fisher, Jed F., Mobashery, Shahriar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304477/
https://www.ncbi.nlm.nih.gov/pubmed/25495032
http://dx.doi.org/10.1021/ja5111706