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Stability of refrigerated miglustat after preparation in InOrpha(®) flavored suspending excipient for compounding of oral solutions and suspensions

BACKGROUND: Miglustat (Zavesca(®)) is an oral treatment for type 1 Gaucher disease and Niemann–Pick disease type C. Patients with Niemann–Pick disease type C often have difficulties swallowing, and miglustat has an unpleasant taste. The stability of miglustat at 2°C–8°C prepared in InOrpha(®) suspen...

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Detalles Bibliográficos
Autores principales: Riahi, Sofyen, Ambühl, Michael, Stichler, Jürgen, Bandilla, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304488/
https://www.ncbi.nlm.nih.gov/pubmed/25632223
http://dx.doi.org/10.2147/DDDT.S74497