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Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake

The efficient delivery of chemotherapeutics to the tumor via nanoparticle (NP)-based delivery systems remains a significant challenge. This is compounded by the fact that the tumor is highly dynamic and complex environment composed of a plurality of cell types and extracellular matrix. Since glycosa...

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Detalles Bibliográficos
Autores principales: Lamichhane, Surya P, Arya, Neha, Ojha, Nirdesh, Kohler, Esther, Shastri, V Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304601/
https://www.ncbi.nlm.nih.gov/pubmed/25632234
http://dx.doi.org/10.2147/IJN.S73508