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Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells

BACKGROUND: Histone deacetylase inhibitors (HDACi’s) are emerging as promising anticancer drugs alone or in combination with chemotherapy or radiotherapy agents. Previous research suggests that HDACi’s have a high degree of selectivity for killing cancer cells, but little is known regarding the impa...

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Detalles Bibliográficos
Autores principales: Li, Liping, Sun, Youxiang, Liu, Jiangqin, Wu, Xiaodan, Chen, Lijun, Ma, Li, Wu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304611/
https://www.ncbi.nlm.nih.gov/pubmed/25592494
http://dx.doi.org/10.1186/s12858-014-0030-5