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MicroRNA miR-466 inhibits Lymphangiogenesis by targeting prospero-related homeobox 1 in the alkali burn corneal injury model

BACKGROUND: Lymphangiogenesis is one of the major causes of corneal graft rejection. Among the lymphangiogenic factors, vascular endothelial growth factor (VEGF)-C and -D are considered to be the most potent. Both bind to VEGF receptor 3 (VEGFR3) to activate Prospero homeobox 1 (Prox1), a transcript...

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Detalles Bibliográficos
Autores principales: Seo, Minkoo, Choi, Jun-Sub, Rho, Chang Rae, Joo, Choun-Ki, Lee, Suk Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304626/
https://www.ncbi.nlm.nih.gov/pubmed/25573115
http://dx.doi.org/10.1186/s12929-014-0104-0