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Combining biophysical methods for the analysis of protein complex stoichiometry and affinity in SEDPHAT
Reversible macromolecular interactions are ubiquitous in signal transduction pathways, often forming dynamic multi-protein complexes with three or more components. Multivalent binding and cooperativity in these complexes are often key motifs of their biological mechanisms. Traditional solution bioph...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304681/ https://www.ncbi.nlm.nih.gov/pubmed/25615855 http://dx.doi.org/10.1107/S1399004714010372 |