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Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions

The recent rapid development of single-particle electron cryo-microscopy (cryo-EM) now allows structures to be solved by this method at resolutions close to 3 Å. Here, a number of tools to facilitate the interpretation of EM reconstructions with stereochemically reasonable all-atom models are descri...

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Detalles Bibliográficos
Autores principales: Brown, Alan, Long, Fei, Nicholls, Robert A., Toots, Jaan, Emsley, Paul, Murshudov, Garib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
EM
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304694/
https://www.ncbi.nlm.nih.gov/pubmed/25615868
http://dx.doi.org/10.1107/S1399004714021683