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Systematic analysis of protein–detergent complexes applying dynamic light scattering to optimize solutions for crystallization trials

Detergents are widely used for the isolation and solubilization of membrane proteins to support crystallization and structure determination. Detergents are amphiphilic molecules that form micelles once the characteristic critical micelle concentration (CMC) is achieved and can solubilize membrane pr...

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Detalles Bibliográficos
Autores principales: Meyer, Arne, Dierks, Karsten, Hussein, Rana, Brillet, Karl, Brognaro, Hevila, Betzel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304753/
https://www.ncbi.nlm.nih.gov/pubmed/25615974
http://dx.doi.org/10.1107/S2053230X14027149