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Systematic analysis of protein–detergent complexes applying dynamic light scattering to optimize solutions for crystallization trials
Detergents are widely used for the isolation and solubilization of membrane proteins to support crystallization and structure determination. Detergents are amphiphilic molecules that form micelles once the characteristic critical micelle concentration (CMC) is achieved and can solubilize membrane pr...
Autores principales: | Meyer, Arne, Dierks, Karsten, Hussein, Rana, Brillet, Karl, Brognaro, Hevila, Betzel, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304753/ https://www.ncbi.nlm.nih.gov/pubmed/25615974 http://dx.doi.org/10.1107/S2053230X14027149 |
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