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Lethality of PAK3 and SGK2 shRNAs to Human Papillomavirus Positive Cervical Cancer Cells Is Independent of PAK3 and SGK2 Knockdown

The p21-activated kinase 3 (PAK3) and the serum and glucocorticoid-induced kinase 2 (SGK2) have been previously proposed as essential kinases for human papillomavirus positive (HPV+) cervical cancer cell survival. This was established using a shRNA knockdown approach. To validate PAK3 and SGK2 as po...

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Detalles Bibliográficos
Autores principales: Zhou, Nannan, Ding, Bo, Agler, Michele, Cockett, Mark, McPhee, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304782/
https://www.ncbi.nlm.nih.gov/pubmed/25615606
http://dx.doi.org/10.1371/journal.pone.0117357