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Tau aggregation and its interplay with amyloid-β
Neurofibrillary tangles and amyloid plaques constitute the hallmark brain lesions of Alzheimer’s disease (AD) patients. Tangles are composed of fibrillar aggregates of the microtubule-associated protein tau, and plaques comprise fibrillar forms of a proteolytic cleavage product, amyloid-β (Aβ). Alth...
Autores principales: | Nisbet, Rebecca M., Polanco, Juan-Carlos, Ittner, Lars M., Götz, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305093/ https://www.ncbi.nlm.nih.gov/pubmed/25492702 http://dx.doi.org/10.1007/s00401-014-1371-2 |
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