Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

Dietary effects on tumor biology can be exploited to unravel cancer vulnerabilities. Here, we present surprising evidence for anti-proliferative action of high-calorie-diet (HCD) feeding on KRAS-driven lung tumors. Tumors of mice that commenced HCD feeding before tumor onset displayed defective unfo...

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Detalles Bibliográficos
Autores principales: Ramadori, Giorgio, Konstantinidou, Georgia, Venkateswaran, Niranjan, Biscotti, Tommasina, Morlock, Lorraine, Galié, Mirco, Williams, Noelle S., Luchetti, Michele, Santinelli, Alfredo, Scaglioni, Pier Paolo, Coppari, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305190/
https://www.ncbi.nlm.nih.gov/pubmed/25533479
http://dx.doi.org/10.1016/j.cmet.2014.11.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305190/
https://www.ncbi.nlm.nih.gov/pubmed/25533479
http://dx.doi.org/10.1016/j.cmet.2014.11.020

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