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Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis
Dietary effects on tumor biology can be exploited to unravel cancer vulnerabilities. Here, we present surprising evidence for anti-proliferative action of high-calorie-diet (HCD) feeding on KRAS-driven lung tumors. Tumors of mice that commenced HCD feeding before tumor onset displayed defective unfo...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305190/ https://www.ncbi.nlm.nih.gov/pubmed/25533479 http://dx.doi.org/10.1016/j.cmet.2014.11.020 |