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Nanoscale Distribution of Presynaptic Ca(2+) Channels and Its Impact on Vesicular Release during Development

Synaptic efficacy and precision are influenced by the coupling of voltage-gated Ca(2+) channels (VGCCs) to vesicles. But because the topography of VGCCs and their proximity to vesicles is unknown, a quantitative understanding of the determinants of vesicular release at nanometer scale is lacking. To...

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Detalles Bibliográficos
Autores principales: Nakamura, Yukihiro, Harada, Harumi, Kamasawa, Naomi, Matsui, Ko, Rothman, Jason S., Shigemoto, Ryuichi, Silver, R. Angus, DiGregorio, David A., Takahashi, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305191/
https://www.ncbi.nlm.nih.gov/pubmed/25533484
http://dx.doi.org/10.1016/j.neuron.2014.11.019