Cargando…
Nanoscale Distribution of Presynaptic Ca(2+) Channels and Its Impact on Vesicular Release during Development
Synaptic efficacy and precision are influenced by the coupling of voltage-gated Ca(2+) channels (VGCCs) to vesicles. But because the topography of VGCCs and their proximity to vesicles is unknown, a quantitative understanding of the determinants of vesicular release at nanometer scale is lacking. To...
Autores principales: | Nakamura, Yukihiro, Harada, Harumi, Kamasawa, Naomi, Matsui, Ko, Rothman, Jason S., Shigemoto, Ryuichi, Silver, R. Angus, DiGregorio, David A., Takahashi, Tomoyuki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305191/ https://www.ncbi.nlm.nih.gov/pubmed/25533484 http://dx.doi.org/10.1016/j.neuron.2014.11.019 |
Ejemplares similares
-
The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells
por: Rubio, María E., et al.
Publicado: (2017) -
EGTA Can Inhibit Vesicular Release in the Nanodomain of Single Ca(2+) Channels
por: Nakamura, Yukihiro
Publicado: (2019) -
Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules
por: Fekete, Adam, et al.
Publicado: (2019) -
Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses
por: Guillaud, Laurent, et al.
Publicado: (2017) -
Presynaptic Mechanisms of Lead Neurotoxicity: Effects on Vesicular Release, Vesicle Clustering and Mitochondria Number
por: Zhang, Xiao-lei, et al.
Publicado: (2015)