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Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells

BACKGROUND: Tumour stromal macrophages differentiate to tumour-associated macrophages (TAMs) with characteristics of immunosuppressive M2-type macrophages, having a central role in promoting tumour vascularisation, cancer cell dissemination and in suppressing anti-cancer immune responses. Bisphospho...

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Detalles Bibliográficos
Autores principales: Sousa, Sofia, Auriola, Seppo, Mönkkönen, Jukka, Määttä, Jorma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305237/
https://www.ncbi.nlm.nih.gov/pubmed/25588705
http://dx.doi.org/10.1186/s12885-015-1005-7