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Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells
BACKGROUND: Tumour stromal macrophages differentiate to tumour-associated macrophages (TAMs) with characteristics of immunosuppressive M2-type macrophages, having a central role in promoting tumour vascularisation, cancer cell dissemination and in suppressing anti-cancer immune responses. Bisphospho...
Autores principales: | Sousa, Sofia, Auriola, Seppo, Mönkkönen, Jukka, Määttä, Jorma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305237/ https://www.ncbi.nlm.nih.gov/pubmed/25588705 http://dx.doi.org/10.1186/s12885-015-1005-7 |
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