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Differences in the distribution, phenotype and gene expression of subretinal microglia/macrophages in C57BL/6N (Crb1(rd8/rd8)) versus C57BL6/J (Crb1(wt/wt)) mice

BACKGROUND: Microglia/macrophages (MG/MΦ) are found in the subretinal space in both mice and humans. Our goal was to study the spatial and temporal distribution, the phenotype, and gene expression of subretinal MG/MΦ in mice with normal retinas and compare them to mice with known retinal pathology....

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Detalles Bibliográficos
Autores principales: Aredo, Bogale, Zhang, Kaiyan, Chen, Xiao, Wang, Cynthia Xin-Zhao, Li, Tao, Ufret-Vincenty, Rafael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305240/
https://www.ncbi.nlm.nih.gov/pubmed/25588310
http://dx.doi.org/10.1186/s12974-014-0221-4