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Epigenetic regulation of histone modifications and Gata6 gene expression induced by maternal diet in mouse embryoid bodies in a model of developmental programming

BACKGROUND: Dietary interventions during pregnancy alter offspring fitness. We have shown mouse maternal low protein diet fed exclusively for the preimplantation period (Emb-LPD) before return to normal protein diet (NPD) for the rest of gestation, is sufficient to cause adult offspring cardiovascul...

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Detalles Bibliográficos
Autores principales: Sun, Congshan, Denisenko, Oleg, Sheth, Bhavwanti, Cox, Andy, Lucas, Emma S, Smyth, Neil R, Fleming, Tom P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305257/
https://www.ncbi.nlm.nih.gov/pubmed/25609498
http://dx.doi.org/10.1186/s12861-015-0053-1