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Mertk Deficiency Affects Macrophage Directional Migration via Disruption of Cytoskeletal Organization

Mertk belongs to the Tyro3, Axl and Mertk (TAM) family of receptor tyrosine kinases, and plays a pivotal role in regulation of cytoskeletal rearrangement during phagocytosis. Phagocytosis by either professional or non-professional phagocytes is impaired in the Mertk deficient individual. In the pres...

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Detalles Bibliográficos
Autores principales: Tang, Yong, Wu, Shen, Liu, Qian, Xie, Jiayi, Zhang, Jingxue, Han, Dong, Lu, Qingxian, Lu, Qingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305281/
https://www.ncbi.nlm.nih.gov/pubmed/25617898
http://dx.doi.org/10.1371/journal.pone.0117787