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Mertk Deficiency Affects Macrophage Directional Migration via Disruption of Cytoskeletal Organization
Mertk belongs to the Tyro3, Axl and Mertk (TAM) family of receptor tyrosine kinases, and plays a pivotal role in regulation of cytoskeletal rearrangement during phagocytosis. Phagocytosis by either professional or non-professional phagocytes is impaired in the Mertk deficient individual. In the pres...
Autores principales: | Tang, Yong, Wu, Shen, Liu, Qian, Xie, Jiayi, Zhang, Jingxue, Han, Dong, Lu, Qingxian, Lu, Qingjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305281/ https://www.ncbi.nlm.nih.gov/pubmed/25617898 http://dx.doi.org/10.1371/journal.pone.0117787 |
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