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Arthritis Induces Early Bone High Turnover, Structural Degradation and Mechanical Weakness

BACKGROUND: We have previously found in the chronic SKG mouse model of arthritis that long standing (5 and 8 months) inflammation directly leads to high collagen bone turnover, disorganization of the collagen network, disturbed bone microstructure and degradation of bone biomechanical properties. Th...

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Detalles Bibliográficos
Autores principales: Vidal, Bruno, Cascão, Rita, Vale, Ana Catarina, Cavaleiro, Inês, Vaz, Maria Fátima, Brito, José Américo Almeida, Canhão, Helena, Fonseca, João Eurico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305284/
https://www.ncbi.nlm.nih.gov/pubmed/25617902
http://dx.doi.org/10.1371/journal.pone.0117100