A Human Type 5 Adenovirus-Based Trypanosoma cruzi Therapeutic Vaccine Re-programs Immune Response and Reverses Chronic Cardiomyopathy

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical neglected tropical disease. Specific immunity promotes acute phase survival. Nevertheless, one-third of CD patients develop chronic chagasic cardiomyopathy (CCC) associated with parasite persistence and immunological u...

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Detalles Bibliográficos
Autores principales: Pereira, Isabela Resende, Vilar-Pereira, Glaucia, Marques, Virgínia, da Silva, Andrea Alice, Caetano, Bráulia, Moreira, Otacilio Cruz, Machado, Alexandre Vieira, Bruna-Romero, Oscar, Rodrigues, Maurício Martins, Gazzinelli, Ricardo Tostes, Lannes-Vieira, Joseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305326/
https://www.ncbi.nlm.nih.gov/pubmed/25617628
http://dx.doi.org/10.1371/journal.ppat.1004594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305326/
https://www.ncbi.nlm.nih.gov/pubmed/25617628
http://dx.doi.org/10.1371/journal.ppat.1004594

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