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Evaluation of Antagonistic Effects of Metformin with Cisplatin in Gastric Cancer Cells

Metformin has recently been introduced as an anti-cancer agent. In this study, we evaluated the effect of metformin and metformin/cisplatin on human gastric MKN-45 cell line. When we used metformin alone, it could inhibit proliferation and induce apoptosis, but it diminish anti-proliferative effects...

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Detalles Bibliográficos
Autores principales: Lesan, Vahid, Ghaffari, Seyed H., Salaramoli, Jamile, Heidari, Mansour, Rostami, Masoumeh, Alimoghaddam, Kamran, Ghavamzadeh, Ardeshir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305376/
https://www.ncbi.nlm.nih.gov/pubmed/25642303